Idiopathic elastosis perforans serpiginosa dovemed. A rare skin condition characterized by the development of small, usually red, bumps on the skin. Elastosis perforans serpiginosa with a history of familial involvement. We present the case of a patient with down syndrome and hyperkeratotic papules located on the superior and. He named the lesion keratosis follieularis serpiginosa. Elastosis cutanea envejecimiento prematuro y estrias by. Treatment list for elastosis perforans serpiginosa. It is a rare disorder characterized by transepidermal elimination of altered elastic fibers. Elastosis perforans serpiginosa symptoms, diagnosis.
Dpenicillamine induced elastosis perforans serpiginosa mimicking acne. Jul 01, 2011 rare skin disease in which abnormal elastic tissue fibers, other connective tissue elements and cellular debris are expelled from papillary dermis through epidermis emedicine. Differential diagnosis shall include 1 favreracouchot syndrome nodular elastosis with cysts and comedones that tends to affect bilateral forehead and cheeks due to solar damage. Elastosis perforans serpiginosa eps is a rare skin disorder in which abnormal elastic tissue fibre passes from the papillary dermis inner layer of skin to the epidermis outer layer of skin, described as transepithelial elimination. Elastosis perforans serpiginosa is considered as mild dermatosis, which is not accompanied by involvement of other organs 2. Elastosis perforans serpiginosa disease definition a rare acquired dermis elastic tissue disorder with increased elastic tissue characterized by focal dermal elastosis and transepidermal elimination of abnormal elastic fibers, presenting as small keratotic papules or plaques arranged in groups in serpiginous or annular patterns on the neck. Cutaneous and ocular manifestations of down syndrome. Jan 01, 2020 a rare acquired dermis elastic tissue disorder with increased elastic tissue characterized by focal dermal elastosis and transepidermal elimination of abnormal elastic fibers, presenting as small keratotic papules or plaques arranged in groups in serpiginous or annular patterns on the neck, face, and arms, while other areas are less frequently affected. Dpenicillamine induced elastosis perforans serpiginosa mimicking acne keloidalis nuchae. Elastosis perforans serpiginosa may be distinguished morphologically and histologically from oth. Elastosis perforans serpiginosum accessed 27 august 2018. Elastosis perforans serpiginosa occurs because the epidermis the outer layer of the skin perceives abnormal elastic tissue to be a foreign object, thus responding through an inflammatory attack. Eps is characterized by the presence of multiple tiny.
This process involves unique morphologic alterations of the epidermis, which forms a. Pdf elastosis perforans serpiginosa a rare case report. Elastosis perforans serpiginosa is a rare chronic dermatosis characterized by extrusion of altered elastic fibers through the epidermis. It is also dependent upon the underlying health condition, if any, associated with it. Elastosis perforans serpiginosa is a rare skin disease characterized by transepidermal elimination of abnormal elastic fibers. Elastosis perforans serpiginosa, therapeutics introduction elastosis perforans serpiginosa eps is a rare skin condition characterized by hyperkeratotic papules, transepidermal elimination of abnormal elastic fibers, and focal dermal elastosis. Dermis elastosis perforante serpiginosa information on. Dermis elastosis perforante serpiginosa information on the. Nodular elastosis definition of nodular elastosis by the.
Elastosis perforans serpiginosa is a unique perforating disorder characterized by transepidermal elimination of elastic fibers and distinctive clinical lesions, which are serpiginous in distribution and can be associated with specific diseases. In both cases, the pathological study of the lesions disclosed a reactive perforating. Elastosis perforans serpiginosa synonyms elastoma intrapapillare perforans verruciforme keratosis follicularis serpiginosa serpiginous perforating elastosis perforating elastoma elastoma intrapapillare perforans presentation stereotypical age and sex most common during the second decade of life and in males mostly distribution of lesions symmetric, neck and upper extremities chiefly, but face. The list of acronyms and abbreviations related to eps elastosis perforans serpiginosa. Elastosis perforans serpiginosa eps is a rare skin disease in which abnormal elastic tissue fibers, other connective tissue elements, and cellular debris are expelled from the papillary dermis through the epidermis transepithelial elimination. Outcomesresolutions the prognosis of elastosis perforans serpiginosa depends upon the severity of the condition. Elastosis perforans serpiginosa eps is a chronic and infrequent dermatosis, belonging to the group of primary perforating dermatoses. In 1952 lutz 1 described a peculiar serpiginous keratotie eruption that was present on the sides of the neck of a 21yearold man for 8 years. If you would like a large, unwatermarked image for your web page or.
This sagging skin is defined significantly by the condition of the underlying muscles. Always seek professional medical advice about any treatment or change in treatment plans. Apr 29, 2016 elastosis perforans serpiginosa is an uncommon and chronic dermatosis characterized by transepidermal elimination of abnormal elastic fibers originating in the dermis. Actinic elastosis, also known as solar elastosis, is an accumulation of abnormal elastin elastic tissue in the dermis of the skin, or in the conjunctiva of the eye, which occurs as a result of the cumulative effects of prolonged and excessive sun exposure, a process known as photoaging. It is characterized by the synthesis of anomalous elastic fibres that are eliminated through perf. Treatment has included various modalities and cryotherapy is one of the effective options. Retrogressive change in cutaneous connective tissue resulting in excessive amounts of material which give the. The list of treatments mentioned in various sources for elastosis perforans serpiginosa includes the following list.
Elastosis perforans serpiginosa is a rare primary perforating disorder. This condition classically presents as small papules arranged in serpiginous or annular patterns on the neck, face, arms, or other flexural areas. Diagnosis is based on clinical and histopathologic aspects. Elastosis perforans serpiginosa has also been thought to be resultant of an injured epidermal barrier. Localized idiopathic elastosis perforans serpiginosa effectively treated by the coherent ultrapulse 5000c aesthetic laser. Eps, colagenosis perforante re activa, foliculitis perforante. Report of a family with a chromosomal investigation.
The cause of abnormal elastic tissue is unknown but may be from a genetic mutation or external factors such as penicillamine. Sep 05, 2018 what is the prognosis of elastosis perforans serpiginosa. Mar 06, 2019 elastosis perforans serpiginosa eps is a rare skin disease in which abnormal elastic tissue fibers, other connective tissue elements, and cellular debris are expelled from the papillary dermis through the epidermis transepithelial elimination. You may not embed one of our images on your web page without a link back to our site. Disorders of transepidermal elimination disorders of transepidermal elimination woo, thomas y rasmussen, james e. Benign prostatic hyperplasia with lower urinary tract symptoms. Nodular elastosis article about nodular elastosis by the. Sorry, we are unable to provide the full text but you may find it at the following locations. The code is valid for the year 2020 for the submission of hipaacovered transactions. Elastosis perforans serpiginosa definition of elastosis. Eps is characterized by the presence of multiple tiny papules on the neck or face in a winding pattern. Elastosis perforans serpiginosaelastosis perforans. Pdf elastosis perforans serpiginosa is a rare skin disease characterized by transepidermal elimination of abnormal elastic fibers. Elastosis perforans serpiginosa in association with.
If you would like a large, unwatermarked image for your web page or blog, please purchase the appropriate license. In 1955 miescher further characterized this entity on the pathological findings. Elastosis perforans serpiginosa eps represents a distinct entity within the spectrum of perforating dermatoses. Always seek professional medical advice about any treatment or change in treatment. Transepidermal elimination te is a mechanism whereby foreign or altered constituents can be removed from the dermis. Elastosis perforans serpiginosa eps is a rare chronic perforating dermatosis which was first described in 1953 by lutz. Localized perforating serpiginous elastosis in a patient with down syndrome. Summary elastosis perforans serpiginosa is a rare chronic dermatosis characterized by extrusion of altered elastic fibers through the e pidermis. Low power of histology of elastosis perforans serpiginosa demonstrates a column of keratotic debris forming a focal invagination through a hyperplastic epidermis figure 1. Solar or senile elastosis, elastosis senilis, actinic elastosis. Pathology outlines elastosis perforans serpiginosum. Elastosis definition of elastosis by the free dictionary. Elastosis perforans serpiginosa pathology dermnet nz. Eps present as asymptomatic to pruritic groups of keratotic papules coalescing in a arcuate serpiginous distribution.
Since it was first described by lutz in 1953, eps is. Elastosis perforans serpiginosa article about elastosis. Brightly eosinophilic fibres are seen within the extruded material, mixed with. Dermis solar or senile elastosis information on the. Elasticvan gieson evg staining highlights elastic fibres, so in this condition will show black fibres transgressing through the focus of transepidermal elimination figures 5, 6. Disorders of transepidermal elimination, international.
Elastosis perforans serpiginosa in association with scabies mite. A loss of elasticity tone and firmness in the skin, known as elastosis, is a natural part of the aging process for most people. Skin elasticity is what determines the skins ability to stretch and then return to its normal state. Abnormal skin fibre tissue forms from the inner skin layer to the outer skin layer which in turn causes the top skin layer to respond to it as if it were a foreign particle i. Closer inspection identifies material undergoing transepidermal elimination figure 2. Elastosis perforans serpiginosa is triggered by excess production of. Elastosis perforans serpiginosa is an infrequent skin dermatosis of unknown.
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